CLONING, EXPRESSION, PURIFICATION, AND CHARACTERIZATION OF CLOSTRIDIUM BOTULINUM NEUROTOXIN SEROTYPE F DOMAINS

Cloning, Expression, Purification, and Characterization of Clostridium botulinum Neurotoxin Serotype F Domains

The use of recombinant BoNT domains has been proposed as a means to develop strategies to treat and prevent botulism.Here, details on the molecular cloning, protein expression, purification, and immunoreactivity of BoNT/F domains from Clostridium botulinum are presented.Initially, full-length synthetic genes encoding recombinant BoNT/F domains (cat

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Re-description of the assassin bug species Pygolampis striata Miller, 1940 with new distributional records from Japan and Indonesia (Heteroptera, Reduviidae, Stenopodainae)

Pygolampis striata Miller, 1940 is described based on a single male specimen.However, there are no records of the species since then.Therefore, the females and nymphs have not Serving Trays been described, and knowledge about their habitat is insufficient.This is the first record of the Assassin bug Pygolampis striata Miller, 1940 from Japan and In

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A rare case of multiple paragangliomas in the head and neck, retroperitoneum and duodenum: A case report and review of the literature

Pheochromocytomas and paragangliomas (PGLs) are rare non-epithelial neuroendocrine neoplasms of the adrenal medulla and extra-adrenal paraganglia respectively.Duodenal PGL is quite rare and there are only two previous reports.Herein, we report a case of multiple catecholamines (CAs)-producing PGLs in the middle ear, retroperitoneum, and duodenum, a

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A Drosophila model of dominant inclusion body myopathy type 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects

Individuals with inclusion body myopathy type 3 (IBM3) display congenital joint contractures with early-onset muscle weakness that becomes more severe in adulthood.The disease arises from an autosomal dominant point mutation causing an E706K substitution in myosin heavy chain type IIa.We have previously expressed the corresponding myosin mutation (

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